According to police, the crash happened just before 2:30 a.m New Year's Day on Route 19 less than a mile from Route 58.
Police say 41-year-old Dale M. Donnells of Berwyn Heights, Maryland was driving a pickup truck south in the northbound lanes of Route 19 when he hit a sedan head on.
State Police say Thomas C. Estep, 21, of Norton, Virginia was driving that sedan. They say Estep died at the scene.
According to officials, Donnells was taken to Russell County Medical Center with minor injuries. They say once Donnells was released, state police took him into custody.
Donnells has been charged with DUI and aggravated involuntary manslaughter.
Police say Route 19 was cleared by 7:45 a.m. Sunday.